Biopharmaceutical company MindMed has announced the first topline data from a novel Phase 2 trial testing high doses of LSD as a treatment for anxiety. The results indicate one to two LSD sessions can generate rapid and sustained reductions to anxiety, however, significantly larger trials will be needed to validate these findings.

A small but landmark study published in 2014 is the only modern research to date investigating the potential use of LSD as a treatment for anxiety. That pilot trial looked at the safety and efficacy of LSD-assisted psychotherapy in 12 patients experiencing anxiety associated with life-threatening diseases.

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The results from that earlier study were promising, and a 12-month follow-up investigation suggested the benefits of treatment may be long-lasting. But until now there hasn’t been any further robust research looking at the impact of LSD on anxiety.

Read more: New Atlas