Wonder enzyme may hold the key to longer, healthier lives

In a surprise finding, researchers at the University of Virginia (UVA) found that the role of alcohol dehydrogenase in detoxifying the body

Could an enzyme responsible for breaking down and eliminating booze from our bodies also be able to help us lead longer, healthier lives? Scientists have discovered a molecular mechanism that could offer just that.

In a surprise finding, researchers at the University of Virginia (UVA) found that the role of alcohol dehydrogenase in detoxifying the body of glycerol and glyceraldehyde – the harmful by-products of fat that build up over time – may provide the best approach to not just extending life but aging more healthily.

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“The discovery was unexpected,” said Eyleen Jorgelina O’Rourke, Associate Professor at UVA’s Department of Biology and the UVA School of Medicine’s Department of Cell Biology. “We went after a very well-supported hypothesis that the secret to longevity was the activation of a cell-rejuvenating process named autophagy and ended up finding an unrecognized mechanism of health and lifespan extension.”

Read more: New Atlas