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Mazonakis’ death: The mystery surrounding sedation before plasmapheresis and questions about Midazolam, Anexate and Propofol

New evidence from testimonies and calls to the clinic – What authorities are investigating about the critical minutes before the collapse

Newsroom September 25 10:26

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A significant part of the investigation into the death of Giorgos Mazonakis is now focusing on the substances he is alleged to have been given before plasmapheresis, with authorities seeking answers about exactly what happened during the critical minutes inside the clinic in Kolonaki.

New evidence points to the administration of midazolam for sedation, followed by Anexate as an antidote, while there are also reports that, when the singer was no longer conscious, the word “propofol” was heard inside the clinic.

The final answer is expected from the toxicological and histological examinations.

The key question investigators are being called upon to answer is which substance or substances were administered to the singer, in what quantity and at what point in time, before the plasmapheresis procedure began.

According to information, Giorgos Mazonakis was allegedly administered midazolam, a drug belonging to the benzodiazepine class and used for sedation.

At the same time, according to the same information, he was allegedly given Anexate, or flumazenil, which is an agent that reverses the effects of benzodiazepines.

This detail is considered particularly important, as flumazenil is used to counteract the sedative effects of drugs such as midazolam, while it is not an antidote for propofol.

However, the presence of Anexate alone is not sufficient to establish exactly which substance was administered, as all the available data will have to be assessed by the competent authorities.

The Question of Propofol

At the same time, a second element keeps open the possibility that another sedative substance may also have been used.

According to information from testimonies, a female employee at the clinic allegedly said that, during the critical minutes, she heard the words “sedation” and “propofol.”

Propofol is a powerful intravenous anesthetic and sedative drug used to induce and maintain anesthesia or deeper sedation.

Unlike midazolam, propofol has no specific antidote or reversal agent.

This is why authorities are examining all possibilities: from whether only midazolam was used to whether multiple substances were administered.

The Nurse’s Two Phone Calls

Particular importance in the investigation is being attached to the two phone calls made by the 56-year-old nurse at the clinic after 16:00, when, according to her testimony, the alarm had already been raised.

She testified for approximately four hours before the investigating magistrate and subsequently described what she claims happened that day.

She said the first call was made at approximately 16:10–16:15, at the doctor’s request, in order to determine whether there was an antidote for propofol.

“Ms. Gaka asked me to find out whether there was an antidote for propofol,” she said.

She claimed that she contacted an anesthesiologist, who told her that there was no antidote for propofol, and the information was then passed on to the doctors present at the clinic.

According to her testimony, the second phone call concerned the clinic’s defibrillator, as the device was allegedly not working and instructions were requested on how to use it.

“Everything Was Going Well Until Four”

The nurse described how the situation at the clinic changed at around 16:00.

“Everything was going well until four,” she said, noting that tension and panic then prevailed.

As she said, she remained in an adjacent room where another patient was located and did not have a view of everything taking place in the room where Giorgos Mazonakis was.

She also said that she had seen the singer the previous day, when he had undergone hydrotherapy.

According to her, his condition then was different from previous occasions, as he “seemed to have something on his mind.”

At the same time, she clarified that, according to her, the administration of sedation was not part of the usual procedure for the specific treatments.

Reports About the Time of Arrival and the Room After the Death

In her testimony, the nurse also referred to what she claims happened after the singer’s death.

She claimed that she was asked to give a different arrival time for Giorgos Mazonakis at the clinic.

“She told me to give that particular time. That he arrived around 3 to 3:30, when he had actually arrived at 2,” she said.

Regarding the room after the ambulance service EKAV left, she claimed that some actions were carried out that staff considered part of the procedure, such as making the bed and restoring the defibrillator to its original position.

Regarding the catheters, she said that one remained in place, while she stated that she did not know what happened to the second.

The Timeline of the Fatal Day

Giorgos Mazonakis had visited the clinic on Karneadou Street in Kolonaki on September 9, 2026.

According to the evidence being examined by authorities, he had undergone hydrotherapy the previous day, after which the plasmapheresis procedure was scheduled.

During the procedure, he was allegedly connected to the machine at approximately 14:14.

At 14:25, the machine recorded its first alarm indication, while at 14:37 the blood circulation process began.

A few minutes later, at 14:44 and 14:45, the doctor allegedly took a photograph of the singer while he was unconscious and sent it to an associate.

The machine stopped at 15:22, while according to the evidence being examined, the singer remained connected for approximately another 23 minutes.

At 15:45, new alerts were recorded, followed by attempts to revive him.

Meeting the Hypnotherapist and Change of Plans

As part of the investigation, authorities are also examining the role of hypnotherapist Nasos Komianos, with whom Giorgos Mazonakis had initially been in contact while seeking help with wellness-related issues.

According to the evidence being examined, the singer had initially considered traveling to London for treatments, but eventually turned to the clinic in Kolonaki.

The two men allegedly came into contact through an associate, after which the connection with the doctor was made.

Messages between the hypnotherapist and the doctor have also come under scrutiny, concerning their communication before the singer’s visit to the clinic.

>Related articles

Nurse tells magistrate singer Giorgos Mazonakis was sedated during fatal clinic procedure

Clinic where Mazonakis died secretly ran plasmapheresis at weekends, medical association reveals

Doctor dismissed nurse’s warning in Mazonakis’s final moments, witness claims

The Family’s Position

The family of Giorgos Mazonakis has requested that the toxicological examinations be expedited in order to establish the exact cause of death.

The family’s lawyer, Charalambos Lykoudis, has expressed reservations about the nurse’s testimony, arguing that certain points coincide with the doctor’s defense line.

At the same time, he has left open the possibility that new individuals or additional offenses may emerge from the investigation.

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#Anexate#Giorgos Mazonakis#Midazolam#plasmapheresis#Propofol#toxicological
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