Scientists edit human embryos for first time

Report published in MIT Technology Review

The MIT Technology Review published on Wednesday a news report about the first-known experiment to create genetically modified human embryos in the United States using a gene-editing tool called CRISPR.

Shoukhrat Mitalipov, director of the Oregon Health & Science University’s Center for Embryonic Cell and Gene Therapy, reportedly led the new research. Mitalipov and the university would not confirm details of the research to CNN.

“Results of the peer-reviewed study are expected to be published soon in a scientific journal. No further information will be provided before then,” according to an emailed statement from the university’s press office. Another researcher cited in the MIT report, the Salk Institute’s Jun Wu, did not reply to CNN’s request for comment.

Mitalipov also declined to comment in the MIT Technology Review report, referencing that the research results have not been published yet in a peer-reviewed scientific journal, which is considered the gold standard for scientific research. The author of the MIT report would not confirm to CNN whether he had seen the paper.

Previously, Mitalipov and his colleagues reported the first success in cloning human stem cells in 2013, successfully reprogramming human skin cells back to their embryonic state. In 2007, a research team led by Mitalipov announced they created the first cloned monkey embryo and extracted stem cells from it.

The MIT Technology Review reported that the researchers in Portland, Oregon, edited the DNA of a large number of one-cell embryos, specifically targeting genes associated with inherited diseases in those embryos. The MIT Technology Review could not determine which disease genes had been chosen for editing in the new research.

more at: wtvr.com